Explore New Ambulances by Chassis
When choosing a new ambulance, the chassis is one of the most important decisions you’ll make. It determines how the vehicle performs on the road, how easy it is to service, and how comfortable it is for both patients and crews. That’s why we partner with two of the most trusted names in the industry, Ford and Chevrolet.
Each chassis offers proven reliability, wide service availability across the US, and the strength to handle the demands of pre-hospital patient care and transport. By pairing our standardized ambulance modules with these dependable platforms, we ensure your ambulance delivers consistent performance, long-term value, and the confidence your crew needs on every call.
Which ambulance chassis is right for you?
Explore details for each option.
Ford F-350
The Ford F-350 4×4 chassis is engineered for heavy-duty performance and equipped with Ford’s Ambulance Prep Package. Features include upgraded alternators to support high electrical loads, advanced cooling systems for extended idling, and available 4×4 capability to handle challenging terrain. Together, these features provide crews with durability, off-road access, and confidence on every call.
Ford E-350
Compact yet capable, the Ford E-350 cutaway chassis delivers balanced maneuverability and payload capacity. Ford’s Ambulance Prep Package supports essential EMS equipment with enhanced electrical capacity, heavy-duty suspension, and integrated safety features that keep your crew mission-ready.
Ford E-450
The Ford E-450 chassis offers increased GVWR for operators who need expanded workspace and equipment storage. Ambulance-specific upgrades, such as a reinforced alternator output and transmission cooling, ensure optimal performance in high-volume, demanding service environments.
Chevrolet 3500 HD
Built for strength, the Chevrolet 3500 HD with 4×4 capability is designed to deliver dependable off-road performance and the durability needed for EMS operations. GM’s Ambulance Application enhancements include upgraded alternators, heavy-duty cooling, and specialized suspension components tailored to high-demand service.
Chevrolet G3500
A versatile cutaway chassis that balances maneuverability with payload capacity, the Chevrolet G3500 provides a proven foundation for Type III ambulances. GM’s factory Ambulance Applications ensure the chassis is mission-ready, with electrical, suspension, and cooling upgrades designed for EMS environments.
Chevrolet G4500
The Chevrolet G4500 offers the highest capacity in the GM cutaway lineup, supporting larger patient modules and greater equipment storage. With GM’s ambulance-focused upgrades, it delivers reliability, stability, and long-term value for busy operations that demand more space and durability.
The Ford F-350 chassis is engineered for heavy-duty performance and equipped with Ford’s Ambulance Prep Package. Features include upgraded alternators to support high electrical loads, advanced cooling systems for extended idling, and available 4×4 capability to handle challenging terrain. Together, these features provide crews with durability, off-road access, and confidence on every call.
Compact yet capable, the Ford E-350 cutaway chassis delivers balanced maneuverability and payload capacity. Ford’s Ambulance Prep Package supports essential EMS equipment with enhanced electrical capacity, heavy-duty suspension, and integrated safety features that keep your crew mission-ready.
The Ford E-450 chassis offers increased GVWR for operators who need expanded workspace and equipment storage. Ambulance-specific upgrades, such as a reinforced alternator output and transmission cooling, ensure optimal performance in high-volume, demanding service environments.
Built for strength, the Chevrolet 3500 HD is designed to deliver dependable off-road performance and the durability needed for EMS operations. It’s available in diesel or gas, with both 4×2 and 4×4 options. GM’s Ambulance Application enhancements include upgraded alternators, heavy-duty cooling, and specialized suspension components tailored to high-demand service.
A versatile cutaway chassis that balances maneuverability with payload capacity, the Chevrolet G3500 provides a proven foundation for Type III ambulances. GM’s factory Ambulance Applications ensure the chassis is mission-ready, with electrical, suspension, and cooling upgrades designed for EMS environments.
The Chevrolet G4500 offers the highest capacity in the GM cutaway lineup, supporting larger patient modules and greater equipment storage. With GM’s ambulance-focused upgrades, it delivers reliability, stability, and long-term value for busy operations that demand more space and durability.
Learn more about ambulance chassis options.
What is an ambulance chassis?
An ambulance chassis is a base vehicle, such as a truck or van, upon which the patient care module is built. It includes the engine, frame, wheels, and driver’s cab. The chassis determines how the ambulance drives, its maximum carrying capacity, and its handling in various environments, among other factors.
Which chassis options does Crestline offer?
Our ambulances are available on both Ford and Chevrolet chassis. Options include the Ford F-350, E-350, and E-450, as well as the Chevrolet 3500 HD, G3500, and G4500. Each chassis is purpose-built to deliver the performance, safety, and dependability needed for patient care and transport.
How does the choice of chassis affect ambulance performance?
Your choice of chassis impacts maneuverability, payload, off-road capability, and interior space. For example, truck-style chassis, such as the Ford F-350 or Chevrolet 3500 HD, offer added durability and available 4×4 capability, making them well-suited for challenging terrain and rural environments. Cutaway van chassis, such as the Ford E-450 or Chevrolet G4500, maximizes interior space and storage capacity while maintaining drivability in urban and suburban settings.
Does chassis selection affect ambulance cost?
Yes. Type I ambulances, built on heavy-duty truck chassis (such as the Ford F-350 or Chevrolet 3500 HD), are typically more expensive due to their added durability and available off-road capability. Type III ambulances, built on cutaway van chassis (such as the Ford E-350/E-450 or Chevrolet G3500/G4500), are generally more cost-effective while still providing ample interior space and functionality.
For exact pricing and configuration details, we recommend you contact your local Crestline dealer partner, who can provide a customized quote tailored to your specific needs.
Does chassis choice impact lead time for delivery?
Chassis availability is one of the most significant factors affecting ambulance delivery timelines. Specific Ford or Chevrolet chassis may be in higher demand or limited supply, which can impact production schedules. However, Crestline’s streamlined production process is designed to keep projects on track and help ensure timely delivery.
We encourage you to contact your local Crestline dealer partner for chassis availability and exact lead times.
How do I choose the right ambulance chassis?
Choosing the proper chassis goes beyond size or cost; it’s about selecting a platform your fleet managers and technicians know and can maintain with confidence. Working with a Ford or Chevrolet chassis means your team benefits from familiarity with service procedures and reliable access to replacement parts through established dealer networks. This helps reduce downtime and keeps your ambulances on the road.
Your local Crestline dealer can walk you through the available options, compare Ford and Chevrolet chassis, and help determine the best fit for your operational and budget needs.
Trusted by Ford. Proven by Crestline.
Crestline is a proud member of the Ford Pro Upfitter Program, a certification that recognizes trusted vehicle manufacturers who meet Ford’s highest standards for quality, safety, and integration.
As a certified upfitter, Crestline works closely with Ford engineering teams to ensure every ambulance is built for seamless compatibility, optimal performance, and long-term reliability. This partnership allows Crestline to access technical data, design support, and vehicle-specific guidance directly from Ford — ensuring that our Type I and Type III ambulances meet the same rigorous standards as the chassis they’re built on.
For customers, this means confidence. Each Crestline ambulance built on a Ford chassis delivers dependable performance, precise engineering, and warranty protection backed by both Ford and Crestline. It’s another way we ensure your fleet is safe, reliable, and ready for service when it matters most.
Let us help you choose the right chassis for your new ambulance.
Choosing the right chassis begins with your operational priorities, whether you require off-road durability, additional workspace for your crew, or balanced maneuverability in busy environments. Every Crestline ambulance is built on a trusted Ford or Chevrolet chassis, engineered and factory-prepared for EMS to deliver reliable performance, easy serviceability, and lasting value.
Are you unsure which chassis is the best fit for your fleet? Your local Crestline dealer partner can provide expert guidance, side-by-side comparisons, and personalized support to ensure you select the chassis that meets your needs today and into the future.
